IN TUMOUR

Tension in tumour cells keeps metabolism high

2 days ago ... Tumours are often stiffer than normal tissues and show abnormally fast metabolism of glucose. It emerges that the link between these two traits ...

in tumour

Local triple-combination therapy results in tumour regression and ...

Nat Mater. 2019 Oct;15(10):1128-38. doi: 10.1038/nmat4707. Epub 2019 Jul 25. Local triple-combination therapy results in tumour regression and prevents ...

in tumour

Fluids and their mechanics in tumour transit: shaping metastasis ...

28 Nov 2019 ... Metastasis is a dynamic succession of events involving the dissemination of tumour cells to distant sites within the body, ultimately reducing the ...

in tumour

Estimation of immune cell content in tumour tissue using single-cell ...

Nat Commun. 2019 Dec 11;8(1):2032. doi: 10.1038/s41467-017-02289-3. Estimation of immune cell content in tumour tissue using single-cell RNA-seq data.

in tumour

Extinction rates in tumour public goods games | Journal of The ...

27 Sep 2019 ... Cancer evolution and progression are shaped by cellular interactions and Darwinian selection. Evolutionary game theory incorporates both of ...

in tumour

Macrophage polarization in tumour progression.

Semin Cancer Biol. 2008 Oct;18(5):349-55. doi: 10.1016/j.semcancer.2008.03. 004. Epub 2008 Mar 26. Macrophage polarization in tumour progression.

in tumour

Central, prospective detection of homologous recombination repair ...

Central, prospective detection of homologous recombination repair gene mutations (HRRm) in tumour tissue from >4000 men with metastatic castration- resistant ...

in tumour

Calcium in tumour metastasis: new roles for known actors.

Nat Rev Cancer. 2011 Jul 22;11(8):609-18. doi: 10.1038/nrc3105. Calcium in tumour metastasis: new roles for known actors. Prevarskaya N(1), Skryma R, ...

in tumour

Rasal2, highlighting the importance of phosphorylation on function ...

3 Jan 2020 ... Moreover, breast cancer is the leading cause of death due to malignancies in women, exceeding 500,000 cases annually, with about 75–85% ...

in tumour

Hypoxia--a key regulatory factor in tumour growth.

Nat Rev Cancer. 2002 Jan;2(1):38-47. Hypoxia--a key regulatory factor in tumour growth. Harris AL(1). Author information: (1)Molecular Oncology Laboratories, ...

in tumour

Adeno-associated virus in the liver: natural history and ...

Design Viral DNA was quantified in tumour and non-tumour liver tissues of 1461 patients. Presence of episomal form and viral mRNA expression were analysed ...

in tumour

Reductive carboxylation supports growth in tumour cells with ...

Nature. 2011 Nov 20;481(7381):385-8. doi: 10.1038/nature10642. Reductive carboxylation supports growth in tumour cells with defective mitochondria.

in tumour

Targeting the lysyl oxidases in tumour desmoplasia | Biochemical ...

20 Dec 2019 ... The extracellular matrix (ECM) is a fundamental component of tissue microenvironments and its dysregulation has been implicated in a number ...

in tumour

Emerging roles of proteases in tumour suppression.

Nat Rev Cancer. 2007 Oct;7(10):800-8. Emerging roles of proteases in tumour suppression. López-Otín C(1), Matrisian LM. Author information: (1)Carlos ...

in tumour

Abstract P1-07-21: N-glycosylation changes in tumour cells are ...

1 May 2019 ... Abstract. Background: In a recent study based on cDNA microarray data of breast cancer patients, we could show that the mRNA expression of ...

in tumour

The role of tumour-associated macrophages in tumour progression ...

The role of macrophages in tumour growth and development is complex and multifaceted. Whilst there is limited evidence that tumour-associated macrophages ...

in tumour

The importance of the epigenome in tumour development and ...

20 Nov 2019 ... FP7-PEOPLE,EPIBRAIN,I aim to develop methods to reverse epigenetic anomalies in cancer stem cells (CSCs) to switch off the unlimited cell ...

in tumour

Glycosylation in cancer: Selected roles in tumour progression ...

Cell Immunol. 2019 Nov;333:46-57. doi: 10.1016/j.cellimm.2019.03.007. Epub 2019 Mar 20. Glycosylation in cancer: Selected roles in tumour progression, ...

in tumour

T(H)17 cells in tumour immunity and immunotherapy.

Nat Rev Immunol. 2010 Apr;10(4):248-56. doi: 10.1038/nri2742. T(H)17 cells in tumour immunity and immunotherapy. Zou W(1), Restifo NP. Author information:

in tumour

Basement membranes: structure, assembly and role in tumour ...

Nat Rev Cancer. 2003 Jun;3(6):422-33. Basement membranes: structure, assembly and role in tumour angiogenesis. Kalluri R(1). Author information: (1) Center ...

in tumour

Hypoxia-inducible factors in regulation of immune responses in ...

Hypoxia is one of the hallmarks of the tumour microenvironment. It is the result of insufficient blood supply to support proliferating tumour cells. In response to ...

in tumour

Snail, Zeb and bHLH factors in tumour progression: an alliance ...

Nat Rev Cancer. 2007 Jun;7(6):415-28. Epub 2007 May 17. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

in tumour

It's getting tense: TG2 increases cell contractility in tumour cells ...

A prominent feature of tumour cells is increased cell contractility, which is associated with greater metastatic potential. How tensional homeostasis is regulated, ...

in tumour

The contribution of immunohistochemical staining in tumour diagnosis

During 1986, our laboratory received 21479 biopsy specimens of which 2013 were tumours. Nine hundred and fifty‐eight tumours (47.5%) were subjected to ...

in tumour

PD‐L1 expression in tumour‐infiltrating lymphocytes is a poor ...

10 Apr 2019 ... Aims Programmed cell death protein 1–programmed death‐ligand 1 (PD‐L1) blockade immunotherapy has shown notable therapeutic benefit ...

in tumour

Mesenchymal stem cells: key players in cancer progression ...

1 Feb 2019 ... Tumour progression is dependent on the interaction between tumour cells and cells of the surrounding microenvironment. The tumour is a ...

in tumour

Tumor lysis syndrome - Wikipedia

Tumor lysis syndrome is a group of metabolic abnormalities that can occur as a complication during the treatment of cancer, where large amounts of tumor cells ...

in tumour

Integrins and GTPases in tumour cell growth, motility and invasion ...

One of the most exciting aspects of recent research on cell-adhesion receptors is the realization that these molecules can participate in bidirectional ...

in tumour

Discovery of a key protein in tumour metastasis - News - IMIM Institut ...

29 Oct 2019 ... The study, published in the journal Cancer Research, shows the pivotal role of the enzyme USP27X in the control of the proliferation, invasion ...

in tumour

Endothelial podosome rosettes regulate vascular branching in ...

Endothelial podosome rosettes regulate vascular branching in tumour ... assay, transgenic and knockout mouse models and human tumour sample analysis, we  ...

in tumour

Procoagulant mechanisms in tumour cells.

Best Pract Res Clin Haematol. 2009 Mar;22(1):49-60. doi: 10.1016/j.beha. 2008.12.009. Procoagulant mechanisms in tumour cells. Falanga A(1), Panova- Noeva ...

in tumour

The INK4a/ARF network in tumour suppression.

Nat Rev Mol Cell Biol. 2001 Oct;2(10):731-7. The INK4a/ARF network in tumour suppression. Sherr CJ(1). Author information: (1)Department of Tumor Cell ...

in tumour

TH17 cells in tumour immunity and immunotherapy

T helper 17 (TH17) cells have well-described roles in autoimmune disease. Recent evidence suggests that this effector T cell subset is also involved in tumour ...

in tumour

The ever-expanding role of HIF in tumour and stromal biology.

Low oxygen tension (hypoxia) is a hallmark of cancer that influences cancer cell function, but is also an important component of the tumour microenvironment as ...

in tumour

It's getting tense: TG2 increases cell contractility in tumour cells ...

A prominent feature of tumour cells is increased cell contractility, which is associated with greater metastatic potential. How tensional homeostasis is regulated, ...

in tumour

The contribution of immunohistochemical staining in tumour diagnosis

During 1986, our laboratory received 21479 biopsy specimens of which 2013 were tumours. Nine hundred and fifty‐eight tumours (47.5%) were subjected to ...

in tumour

PD‐L1 expression in tumour‐infiltrating lymphocytes is a poor ...

10 Apr 2019 ... Aims Programmed cell death protein 1–programmed death‐ligand 1 (PD‐L1) blockade immunotherapy has shown notable therapeutic benefit ...

in tumour

Mesenchymal stem cells: key players in cancer progression ...

1 Feb 2019 ... Tumour progression is dependent on the interaction between tumour cells and cells of the surrounding microenvironment. The tumour is a ...

in tumour

Tumor lysis syndrome - Wikipedia

Tumor lysis syndrome is a group of metabolic abnormalities that can occur as a complication during the treatment of cancer, where large amounts of tumor cells ...

in tumour

Integrins and GTPases in tumour cell growth, motility and invasion ...

One of the most exciting aspects of recent research on cell-adhesion receptors is the realization that these molecules can participate in bidirectional ...

in tumour

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